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| Paper |
Radiation Safety Management Vol.1, No.1 (17-20) |
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| High Density 60 Hz Magnetic Field Has No Effects on Mutagenicity and Growth of the Budding Yeast Saccharomyces cerevisiae |
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Kikuo Shimizu1), Yasuo Nakaoka2) and Takayoshi Yamamoto1)
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1) Radioisotope Research Center, Osaka University
2) Division of Biophysical Engineering, Graduate School of Engineering Science, Osaka University
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Received June 10, 2002; accepted September 20, 2002
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| The budding yeast Saccharomyces cerevisiae was used as a model organism to study the effects of 60 Hz magnetic fields on growth and mutagenicity. We designed an extremely low-frequency magnetic field (ELF-MF) exposure system for biological experiments. Using this system, we studied the effect of the ELF-MF on various yeast strains including radiation-sensitive mutants, rad and rev. The exposure to 60Hz magnetic fields of up to 0.5T had no effect on yeast cell growth. Neither a mutagenic potential of 60Hz nor static magnetic fields of up to 0.5 T could be detected by ade2→ADE2+ reversion assay. |
| Key words: |
ELF, Leningrad test, yeast, mutation frequency |
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